University of Kashan Iranian Journal of Mathematical Chemistry 2228-6489 10 1 2019 03 01 Aromaticity of fullerenes, the Way to their Functionalization (Review) 71 91 87580 10.22052/ijmc.2019.174207.1430 EN B. Szefler Department of Physical Chemistry, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Kurpińskiego 5, Bydgoszcz 85-096, Poland R. Pop University of Medicine and Pharmacy, Romania Journal Article 2019 02 06 Aromaticity is used to describe the durability and reactivity of structures containing delocalized  electrons.In this review article, the aromaticity of fullerenes patched with flowers of 6-and 8-membered ringsis discussed, optimized at the HF and DFT levels of theory, in terms of HOMA and NICS criteria. The aromatic character of these nanostructures allows for functionalization and finally for increasing their solubility in polar solvents. The overall conclusion is that several of the yet hypothetical molecular nanostructures herein described are serious candidates for new medicinal products, as a proposal for personalized medicine. https://ijmc.kashanu.ac.ir/article_87580_d95a512ef99af03fb694424430d68f69.pdf